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Biology of the CRISPR/Cas9 system and relevant transcription/translation products. Engineered CRISPR/Cas9 system can be devised for site‐specific genome editing as sgRNA:Cas9. Abbreviations: Cas9, CRISPR associated protein 9; CRISPR, clustered regularly interspaced short palindromic repeats; tracrRNA, trans‐activating CRISPR RNA; Rec, recognition; Nuc, nuclease; sgRNA, single‐guide RNA
