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. 2022 Oct 9;42(12):1257–1287. doi: 10.1002/cac2.12366

FIGURE 4.

FIGURE 4

Formation of a DSB and repair by NHEJ and HDR. Repair by NHEJ results in the formation of random indels. Repair by HDR requires a template DNA strand for precise repair. Abbreviations: DSB, double‐stranded break; HDR, homology‐directed repair; NHEJ, non‐homologous end joining