Table 3.
Anti-SARS-CoV-2 immune response in general population in 2022
Parameter | All Subjects (n = 2,179) |
Men (n = 866, 39.7%) |
Women (n = 1,173, 60.3%) |
---|---|---|---|
Anti-SARS-CoV-2 immune response | |||
Spike protein antibodies, U/L | 2,065 (153-13,033) | 2,194 (129-13,662) | 1,710 (130-11,338)** |
Neutralizing antibodies, AU/mL | 2.68 (1.35-12.68) | 2.80 (1.33-15.12) | 2.52 (1.33-11.53)** |
# Median values ± interquartile range (IQR). The median age and IQR was 61.0 (49.0-72.0) years. Spearman correlations between spike protein and neutralizing antibody levels were 0.75 in men and 0.76 in women, respectively, p<0.0001. The percentage of all subjects, men, and women with positive values for S protein antibody (>0.80 U/L) were 86.3%, 85.0%, and 85.6%, while for neutralizing antibody (>1.0 AU/mL) these percentages were 68.0%, 62.6%, and 68.2%. All samples with S protein antibody values ≥250 U/L were diluted 1:100 so that values of up to 25,000 U/L could be reported. **Median values in women were significantly lower (P<0.001) than values in men.