Table 1.
Baseline characteristics of the study population
| Total (n = 485) | Single-vessel CAD (n = 116) | Multi-vessel CAD (n = 369) | P-value | |
|---|---|---|---|---|
| Age (years) | 60 (52, 67) | 57 (52, 65) | 61 (52.50, 67) | 0.028 |
| Male (n, %) | 359 (74%) | 86 (74.10%) | 273 (74%) | 0.974 |
| BMI (kg/m2) | 25.69 (23.53, 27.98) | 25.24 (22.52, 26.82) | 25.95 (23.88. 28.33) | < 0.001 |
| DM (n, %) | 185 (38.10%) | 21 (18.10%) | 164 (44.40%) | < 0.001 |
| Smoking (n, %) | 200 (41.20%) | 56 (48.30%) | 144 (39%) | 0.077 |
| Drinking (n, %) | 67 (13.80%) | 18 (15.50%) | 49 (13.30%) | 0.542 |
| Hypertension (n, %) | 225 (46.40%) | 41 (35.30%) | 184 (49.90%) | 0.006 |
| HbA1c (%) | 6.10 (5.70, 7) | 5.80 (5.50, 6.30) | 6.20 (5.70, 7.40) | < 0.001 |
| FPG (mmol/l) | 7.47 (6.21, 10.14) | 6.89 (5.99, 8.10) | 7.68 (6.29, 10.68) | < 0.001 |
| TC (mmol/l) | 4.76 (3.98, 5.60) | 4.76 (4.30, 5.49) | 4.77 (3.94, 5.65) | 0.684 |
| TG (mmol/l) | 1.31 (0.94, 1.81) | 1.15 (0.82, 1.53) | 1.38 (0.97, 1.89) | < 0.001 |
| HDL-C (mmol/l) | 1.12 (0.93, 1.29) | 1.23 (1.06, 1.36) | 1.08 (0.91, 1.26) | < 0.001 |
| LDL-C (mmol/l) | 3.20 (2.48, 3.86) | 3.24 (2.66, 3.77) | 3.18 (2.41, 3.91) | 0.636 |
| UA (umol/l) | 368.90 (306.15, 448.95) | 353.60 (301.45, 419.53) | 376.70 (307.25, 458) | 0.053 |
| LAD (mm) | 35.60 (32.50, 38.30) | 34.20 (31.60, 36.50) | 35.80 (32.90, 38.70) | 0.001 |
| LVDd (mm) | 46.60 (43.60, 49.70) | 46.60 (43.30, 48.80) | 46.60 (43.80, 50.13) | 0.156 |
| LVDs (mm) | 29.60 (25.60, 33.55) | 29.40 (25, 32.80) | 29.60 (25.90, 33.90) | 0.271 |
| IVS (mm) | 10.80 (10.10, 11.60) | 10.60 (9.90, 11.30) | 10.90 (10.10, 11.80) | 0.010 |
| LVPW (mm) | 10.50 (10, 11.20) | 10.30 (10, 10.80) | 10.50 (10, 11.23) | 0.020 |
| LVEF (%) | 59 (52.45, 62) | 58.80 (54.10, 62) | 59.10 (52, 62) | 0.706 |
| BNP (pg/ml) | 551 (165.50, 1514) | 327.50 (137.50, 928) | 702 (190.50, 1726.50) | 0.001 |
| D-dimer (ug/ml) | 94 (52.50, 175) | 86.50 (48, 188.25) | 96 (56.50, 172.50) | 0.319 |
| CRP (mg/l) | 6.14 (2.02, 13.20) | 5.53 (1.63, 12.94) | 6.36 (2.25, 13.23) | 0.368 |
| Cr (umol/l) | 77 (65, 92) | 75 (64.25, 85.75) | 78 (65.50, 95) | 0.057 |
| TyG index | 9.01 (8.65, 9.41) | 8.77 (8.42, 9.06) | 9.09 (8.71, 9.52) | < 0.001 |
| TyG-BMI index | 231.59 (210.41, 256.57) | 213.89 (195.09, 237.29) | 236.59 (213.63, 261.54) | < 0.001 |
| TG/HDL-C ratio | 2.65 (1.83, 3.99) | 2.14 (1.53, 2.95) | 3.04 (1.89, 4.27) | < 0.001 |
| METS-IR | 41.38 (37.20, 46.38) | 38.22 (34.20, 41.91) | 42.91 (37.93, 47.55) | < 0.001 |
Data are presented as median (interquartile range) or number (proportion, %)
CAD, Coronary artery disease; BMI, body mass index; DM, diabetes mellitus; FPG, fasting plasma glucose; HbA1c, glycated hemoglobin A1c; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; UA, uric acid; LAD, left atrial diameter; LVDd, left ventricular end diastolic diameter; LVDs, left ventricular systolic diameter; IVS, interventricular septal thickness; LVPW, left posterior wall thickness; LVEF, left ventricular ejection fraction; BNP, B-type natriuretic peptide; CRP, C-reactive protein; Cr, creatinine; TyG index, triglyceride and glucose index; TyG-BMI index, triglyceride glucose-body mass index; TG/HDL-C ratio, triglyceride to high-density lipoprotein cholesterol ratio; METS-IR, metabolic score for insulin resistance