Table 2.

Performance comparison of the predictive models in the development cohort

Model	AUC (95% CI)	P-value	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)
ADC	0.779 (0.696–0.848)	0.025	83.3	65.6	43.1	92.6
DWI	0.768 (0.684–0.838)	0.039	60.0	86.5	58.1	87.4
Combined	0.848 (0.774–0.906)	0.315	83.3	72.9	49.0	93.3
Nomogram	0.890 (0.821–0.938)	Reference	73.3	93.8	78.6	91.8

AUC Area under the curve; CI Confidence interval; PPV Positive predictive value; NPV Negative predictive value; ADC Apparent diffusion coefficient; DWI Diffusion-weighted imaging

P < 0.05 indicates statistically significant