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. 2022 Dec 17;20:489. doi: 10.1186/s12916-022-02690-w

Table 2.

Risk of bias assessment of observational studies

Authors Item 1 Item 2 Item 3 Item 4 Item 5 Item 6 Item 7 Item 8 Item 9 Total
Abelman et al. 2020 [25] N Y N Y Y Y Y N N 5
Castro-Sanchez et al. 2018 [35] N Y N Y Y Y Y N N 5
Cutler et al. 2016 [36] N Y N Y Y N Y N N 4
Dominick et al. 2015 [18] Y Y N Y Y Y Y Y Y 8
Franca et al. [37] N N N N Y Y Y N N 3
Guth et al. 2016 [38] N Y N Y Y Y Y N N 5
Hadnott et al. 2019 [23] Y Y Y Y Y Y Y N N 7
Johansen et al. 2017 [39] N Y N Y Y Y Y N N 5
Knight et al. 2014 [40] N N N N N Y Y N N 2
Lakhdissi et al. 2017 [41] N N N N N Y Y N N 2
Madrigal et al. 2019 [42] N N N Y Y Y Y N N 4
Maslow et al. 2014 [43] N Y N Y Y Y Y Y Y 7
Massarotti et al. 2021 [34] N Y N N Y Y Y N N 4
McLean et al. 2014 [44] N Y N Y N N N Y N 3
Mody et al. 2019 [26] Y Y N Y Y Y Y N N 6
Patel et al. 2015 [45] N N N Y Y Y N N N 3
Patel et al. 2009 [33] N N N Y Y Y N N N 3
Quinn et al. 2014 [46] Y Y Y Y Y Y Y N N 7

Item 1: Was the sample representative of the target population?

Item 2: Were the study participants recruited in an appropriate way?

Item 3: Was the sample size adequate?

Item 4: Were the study subjects and the setting described in detail?

Item 5: Was the data analysis conducted with sufficient coverage of the identified sample?

Item 6: Were objective, standard criteria used for the measurement of the condition?

Item 7: Was the condition measured reliably?

Item 8: Was there an appropriate statistical analysis?

Item 9: Are all important confounding factors/subgroups identified and accounted?