Table 4.

Secondary Objective - Propensity Score Matched Rate of SALI and Hazard Ratios Among Statin Initiators and Non-Statin Initiators

Overall Results	Optum		MarketScan		Overall
	Non-Statin Initiators	Statin Initiators	Non-Statin Initiators	Statin Initiators	Non-Statin Initiators	Statin Initiators
No of patients	287,655	82,451	229,545	66,959	517,200	149,410
No of person-years	509,467	89,844	392,691	71,099	902,158	160,943
No of SALI	112	13	112	19	224	32
Rate of SALI per 100,000 person years	22	14	29	27	25	20
HR (95% CI)	Ref	0.59 (0.33, 1.06)	Ref	0.91 (0.56, 1.50)	Ref	0.76 (0.52, 1.11)

Abbreviations: SALI, severe acute liver injury; HR, hazard ratio; CI, confidence interval.