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. 2022 Oct;76(5):329–332. doi: 10.5455/medarh.2022.76.329-332

Table 2. Characteristics of baseline laboratory indices in metformin or insulin users.

Characteristics Non-metformin (N =16) Metformin (N =25) P-value Non-insulin (N = 10) Insulin (N = 35) P-value
Concentrations (per day) - 1 (0.55 – 1.52) NA - 35 (28.2 – 50.3) NA
Age (years) 58.67 ± 10.81 60.80 ± 12.56 0.518 52.67 ± 8.81 67.8 ± 9.26 0.038
Gender (M, %) 7 (43.7 %) 12 (48 %) 0.657 6 (60 %) 17 (48.5 %)
Comorbidities (n, %)
Hypertension 7 (43.7%) 7 (28 %) 0.257 3 (30 %) 9 (25.7%) 0.436
Cardiovascular disease 2 (12.5%) 4 (16 %) 0.368 1 (10%) 5 (14.2 %) 0.813
Chronic kidney disease 7 (43.7 %) 7 (28 %) 0.537 4 (40 %) 10 (28.5%) 0.251
Baseline laboratory indices
Blood glucose 7 (5-14) 10 (8-14) 0.014 5 (4-8) 14 (9-15) < 0.001
White blood cells 8 (6-12) 9 (6-10) 0.463 7 (5-11) 9 (7-12) 0.082
Lymphocytes 1 (1-1) 1 (1-1) 0.666 1 (1-2) 1 (1-1) 0.430
Monocytes 0 (0-0) 0 (0-0) 0.040 0 (0-0) 0 (0-0) 0.368
Neutrophils 7 (5-11) 7 (4-9) 0.315 6 (4-8) 9 (6—11) 0.022
Creatinine 102 (86-119) 105 (90-124) 0.644 102 (86-118) 102 (87-127) 0.647
CRP 52 (22-121) 24 (15-58) 0.046 40 (16-104) 43 (18-100) 0.846
D-dimer 1 (0-3) 1 (0-3) 0.544 1 (0-3) 2 (1-3) 0.181
PCT 0 (0-1) 0 (0-1) 0.660 0 (0-1) 0 (0-1) 0.340
COVID-19 treatment protocols
Antibiotics (n, %) 13 (81.2 %) 14 (56 %) 0.486 8 (80%) 25 (71.4%) 0.587