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. 2022 Dec 19;24:72. doi: 10.1186/s12968-022-00901-0

Table 5.

Subgroup analysis of virally supressed individuals (< 200 copies/ml after the initiation on ART)

Parameter Virally supressed group Virally supressed group p value
n = 58 n = 58
(Naïve) (ART)
CD4 count (cells/μl) 292 (152 to 432) 378 (274 to 633) < 0.001
CD8 count (cells/μl) 789 (575 to 1044) 608 (456 to 821) < 0.001
HIV viral load (copies/ml) 85,320 (11,604 to 298,008) 20* (20* to 22) < 0.001
HIV viral load (log copies/ml) 4.9 (4.1 to 5.5) 1.3* (1.3* to 1.3*) < 0.001
Presence of pericardial effusion 39 (67%) 35 (60%) 0.6
Global T2 SIR 1.5 ± 0.2 1.5 ± 0.2 0.5
Global native T1 mapping (ms) 1030 ± 48 1009 ± 31 < 0.001
Global native T2 mapping (ms) 48 ± 3 48 ± 2 0.2
Global ECV (%) 26 ± 4 24 ± 3 0.006
EGE 4.1 ± 2.8 3.7 ± 2.3 0.4
LGE present 28 (48%) 31 (53%) 0.5

Bold values indicate p value of ≤ 0.05

Continuous variables are mean ± standard deviation or median (interquartile range) unless otherwise specified

LV left ventricle, RV right ventricle, SIR Signal intensity ratio, ECV Extracellular volume, LGE late gadolinium enhancement

*20 copies/ml (log = 1.3) is the lower limit of measurement for our HIV-1 assay