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. 2023 Jan 1;19(1):156–166. doi: 10.7150/ijbs.76148

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Competition of 5a-NOTA-¹⁸F uptake by unlabeled peptide 5a in the subcutaneous BxPC-3 tumor model. BxPC-3 tumors-bearing NGS mice were injected i.v. with or without unlabeled 5a (130 nmol/mouse, Competitor) and 10 min later, with 5a-NOTA-¹⁸F (~ 3 MBq/animal, i.v.). Radiotracer uptake was assessed after 2 h by whole-body PET/CT (A, B) or with a gamma-counter for biodistribution studies (C). Bars, mean ± SE (n=3 mice). Arrow, BxPC-3 tumor. *, P<0.05, **, P<0.01 and ***P<0.001 by two-tail t-test.