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. 2023 Jan 1;19(1):89–103. doi: 10.7150/ijbs.74227

Figure 1.

Figure 1

miR-1275 was significantly downregulated in chemoresistant BC patients and acted as a prognostic factor. A. Comparison of expression levels of miR-1275 in different time points during NCT between the Low-R group (Miller-Payne grades 1 and 2) and the High-R group (Miller-Payne grades 3, 4 and 5). B. Comparison of expression levels of miR-1275 in different response groups during NCT. C. The expression levels of miR-1275 in BC cell lines and cellular supernatants. D. The correlation between miR-1275 expression and the IC50 value of epirubicin in 29 breast cancer cell lines in the CCLE and GDSC databases. E. Data of miR-1275 was obtained from the TCGA database. Lower expression of miR-1275 was correlated with a worse overall survival in patients with LABC. *p < 0.05, **p<0.01, ***p < 0.001. The data expressed as the mean ± SD.