Table 3.
Spearman's rank correlation coefficient between NDRG1, p-NDRG1 (Thr346), TGFβ1, and p-GSK3β (Tyr216) staining
| TGFβ1 | TGFβ1 (M) |
TGFβ1 (C) |
TGFβ1 (N) |
NDGR1 | NDGR1 (M) |
NDGR1 (C) |
NDGR1 (N) |
p-NDGR1 | p-NDGR1 (M) | p-NDGR1 (C) | p-NDGR1 (N) | p-GSK3β | p-GSK3β (C) |
p-GSK3β (N) |
||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TGFβ1 | ρ | 1.000 | 0.247 | 0.992 | 0.083 | 0.205 | 0.060 | 0.182 | 0.282 | 0.128 | 0.050 | 0.145 | 0.020 | 0.092 | 0.094 | 0.053 |
| P | 0.042* | <0.001* | 0.503 | 0.092 | 0.625 | 0.135 | 0.019* | 0.298 | 0.688 | 0.239 | 0.869 | 0.453 | 0.443 | 0.664 | ||
| TGFβ1 (M) |
ρ | 1.000 | 0.213 | 0.356 | 0.218 | 0.099 | 0.262 | 0.190 | 0.220 | -0.105 | 0.253 | 0.147 | -0.009 | 0.020 | -0.139 | |
| P | 0.081 | 0.003* | 0.073 | 0.420 | 0.031* | 0.121 | 0.074 | 0.396 | 0.039* | 0.236 | 0.945 | 0.872 | 0.258 | |||
| TGFβ1 (C) |
ρ | 1.000 | 0.088 | 0.259 | 0.055 | 0.232 | 0.286 | 0.195 | 0.048 | 0.213 | 0.059 | 0.110 | 0.115 | 0.047 | ||
| P | 0.477 | 0.033* | 0.654 | 0.057 | 0.018* | 0.113 | 0.697 | 0.083 | 0.634 | 0.370 | 0.352 | 0.706 | ||||
| TGFβ1 (N) |
ρ | 1.000 | -0.018 | 0.167 | -0.074 | -0.071 | -0.079 | -0.068 | -0.050 | -0.023 | -0.181 | -0.248 | 0.108 | |||
| P | 0.886 | 0.173 | 0.550 | 0.563 | 0.526 | 0.586 | 0.690 | 0.852 | 0.139 | 0.041* | 0.379 | |||||
| NDGR1 | ρ | 1.000 | 0.447 | 0.823 | 0.525 | 0.660 | 0.002 | 0.630 | 0.473 | 0.264 | 0.320 | 0.012 | ||||
| P | <0.001* | <0.001* | <0.001* | <0.001* | 0.987 | <0.001* | <0.001* | 0.025* | 0.006* | 0.918 | ||||||
| NDGR1 (M) |
ρ | 1.000 | 0.153 | 0.037 | 0.260 | 0.251 | 0.287 | 0.210 | 0.085 | 0.142 | -0.014 | |||||
| P | 0.190 | 0.756 | 0.026* | 0.031 | 0.013* | 0.072 | 0.477 | 0.234 | 0.907 | |||||||
| NDGR1 (C) |
ρ | 1.000 | 0.344 | 0.628 | -0.126 | 0.592 | 0.472 | 0.296 | 0.310 | 0.094 | ||||||
| P | 0.002* | <0.001* | 0.284 | <0.001* | <0.001* | 0.011* | 0.008* | 0.433 | ||||||||
| NDGR1 (N) |
ρ | 1.000 | 0.424 | 0.041 | 0.285 | 0.410 | 0.150 | 0.159 | 0.045 | |||||||
| P | <0.001* | 0.727 | 0.014* | <0.001* | 0.209 | 0.181 | 0.710 | |||||||||
| p-NDGR1 | ρ | 1.000 | 0.161 | 0.904 | 0.682 | 0.468 | 0.510 | 0.127 | ||||||||
| P | 0.162 | <0.001* | <0.001* | <0.001* | <0.001* | 0.291 | ||||||||||
| p-NDGR1 (M) | ρ | 1.000 | 0.109 | 0.094 | 0.178 | 0.163 | 0.150 | |||||||||
| P | 0.346 | 0.418 | 0.137 | 0.175 | 0.213 | |||||||||||
| p-NDGR1 (C) | ρ | 1.000 | 0.444 | 0.395 | 0.463 | -0.051 | ||||||||||
| P | <0.001* | 0.001* | <0.001* | 0.673 | ||||||||||||
| p-NDGR1 (N) | ρ | 1.000 | 0.470 | 0.413 | 0.329 | |||||||||||
| P | <0.001* | <0.001* | 0.005* | |||||||||||||
| p-GSK3β | ρ | 1.000 | 0.952 | 0.314 | ||||||||||||
| P | <0.001* | 0.007* | ||||||||||||||
| p-GSK3β (C) |
ρ | 1.000 | 0.122 | |||||||||||||
| P | 0.307 | |||||||||||||||
| p-GSK3β (N) |
ρ | 1.000 | ||||||||||||||
| P | ||||||||||||||||
ρ: Spearman's rank correlation coefficient; P: bilateral significance; M: membrane; C: cytoplasm; N: nucleus.
Bold numbers indicate statistically significant ρ.