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. 2023 Jan 1;19(1):34–49. doi: 10.7150/ijbs.72381

Figure 1.

Figure 1

KMT2B is upregulated in CC and associated with poor prognosis. (A) The mRNA levels of KMT2B in CC (n = 24), adjacent non-tumor tissues (n = 28), and 9 CC cell lines obtained from the GEO profile. (B) Representative IHC images of KMT2B in CC tissues and adjacent nontumor cervical tissues. Scale bars, 10×, 250 µm; 40×, 50 µm; (C) IHC scores of KMT2B staining in CC tissues and matched adjacent nontumor tissues (n = 30). (D) Relative mRNA expression of KMT2B in CC cells (HeLa and C-33A) and normal cervical cells (HcerEpic) measured by qPCR (n = 3). The overall survival analysis (E) and relapse-free survival analysis (F) of CC patients based on the data from TCGA database using the web-accessible Kaplan-Meier plotter. Survival curves were calculated using the Kaplan-Meier method and analyzed by the log-rank test. *, p < 0.05, **, p < 0.01, ***, p < 0.001.