Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Three main pathways of ceramides synthesis in mammals. Ceramide is synthesized in three main ways, with de novo pathway occurring primarily in the endoplasmic reticulum, sphingomyelinase pathway occurring primarily in the lysosome, and salvage pathway occurring primarily in the Golgi apparatus. The three modes of synthesis work together to maintain the balance of ceramide metabolism in vivo.
