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. 2023 Jan 1;19(1):331–345. doi: 10.7150/ijbs.72538

Figure 6.

Figure 6

BST2 promotes CRC progression and TAMs infiltration in vivo. A IHC staining of BST2, TAMs (for the M2 macrophage marker CD163), T cells (CD3) and MDSCs (CD33) in high- and low-BST2 groups. Scale bar=50 μm. B The quantitative analysis of IHC staining. C-E The tumor size and survival rate of subcutaneous tumor models in the control and BST2 knockdown groups. F-G The flow cytometry analysis for the comparison of infiltrated TAMs isolated from subcutaneous tumors between control and BST2 knockdown groups. H-J The size of subcutaneous tumors and survival rate of mouse models in the control and BST2 overexpressed groups. K-L The flow cytometry analysis for the comparison of infiltrated TAMs isolated from subcutaneous tumors between control and BST2 overexpressed groups. Error bars, SD, *P < 0.05; ***P < 0.001 ****P < 0.0001; ns, not significant.