Table 5.

Comparison between patients with mastocytosis and monoclonal mast cell activation syndrome who reacted with NSAIDs in the Swedish cohort.

	Mastocytosis with NSAID hypersensitivity reaction (n = 13)	MMAS with NSAID hypersensitivity reaction (n = 5)	p-valuea
Age at diagnosis, median (range)	50 (22–66)	55 (36–66)	0 . 430 b
Male gender, n (%)	5 (38.5)	1 (20.0)	0 . 615 a
Presence of atopy, n (%)	1 (7.7) (1 NA)	1 (20.0) (1 NA)	0 . 450 a
Presence of asthma and/or rhinitis, n (%)	2 (15.4)	2 (40.0) (1 NA)	0 . 516 a
Total IgE levels (kU/l), median (range)	11.5 (4–280) (1 NA)	170 (82–250)	<0 . 01 b
Baseline tryptase levels (ng/ml), median (range)	34 (8–530)	17 (4–21)	0 . 217 b

Abbreviations: NSAID, non-steroidal anti-inflammatory drug; MMAS, monoclonal mast cell activation syndrome NA = not analysed.

^a p-values were calculated using Fisher's exact test;.

^b p-values were calculated using a 2-tailed Mann-Whitney U-test; Bold indicates statistical significance (p < 0.05).