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. 2022 Dec 5;9:1009765. doi: 10.3389/fcvm.2022.1009765

TABLE 3.

The prognostic impacts of metastatic sites on patients with primary malignant cardiac tumors.

OS CSS


Variable HR (95% CI) P value HR (95% CI) P value
Unadjusted HR
Metastasis site 0.75 0.63
   Bone Reference Reference
   Brain 1.72 (0.62–4.77) 0.29 1.96 (0.69–5.53) 0.21
   Liver 1.12 (0.47–2.70) 0.79 1.13 (0.45–2.86) 0.79
   Lung 1.26 (0.62–2.58) 0.53 1.27 (0.60–2.70) 0.54
Model 1*
Metastasis site 0.24 0.19
   Bone Reference Reference
   Brain 3.20 (1.02–10.00) 0.046 3.53 (1.09–11.47) 0.036
   Liver 1.34 (0.53–3.42) 0.53 1.30 (0.49–3.45) 0.60
   Lung 1.67 (0.75–3.71) 0.21 1.60 (0.69–3.72) 0.27
Model 2
Metastasis site 0.24 0.20
   Bone Reference Reference
   Brain 3.23 (1.01–10.28) 0.047 3.53 (1.07–11.69) 0.039
   Liver 1.36 (0.52–3.56) 0.53 1.30 (0.47–3.56) 0.62
   Lung 1.69 (0.74–3.87) 0.21 1.60 (0.67–3.83) 0.29
Model 3
Metastasis site 0.23 0.21
   Bone Reference Reference
   Brain 3.30 (1.03–10.60) 0.045 3.52 (1.05–11.75) 0.041
   Liver 1.37 (0.52–3.57) 0.52 1.30 (0.47–3.56) 0.62
   Lung 1.67 (0.73–3.82) 0.23 1.60 (0.67–3.85) 0.29

*HR were adjusted for age at diagnosis, median household income, histopathology, and size.

HR were adjusted for age at diagnosis, median household income, histopathology, size, and sex.

HR were adjusted forage at diagnosis, median household income, histopathology, size, sex, and surgery.

OS, overall survival; CSS, cancer specific survival; HR, hazard ratio; CI, confidence interval.