TABLE 3.

Cardiovascular disease mortality according to quartiles of serum lycopene concentrations among patients with CKD.

	Quartiles of serum lycopene level (μg/dl)
	Quartiles 1	Quartiles 2	Quartiles 3	Quartiles 4	P trend
Median (IQR)	8.0 (6.0, 10.0)	16.0 (14.0, 18.0)	25.0 (23.0, 28.0)	42.0 (36.0, 51.3)
Rang	0–12.0	12.0–20.0	20.1–31.9	32.00–151.0
Death (%)	716 (1,970)	571 (1,881)	473 (1,911)	395 (1,921)
Model 1	Reference	0.905 (0.81–1.011)	0.808 (0.718–0.908)	0.806 (0.712–0.913)	< 0.001
Model 2	Reference	0.903 (0.808–1.01)	0.806 (0.716–0.909)	0.784 (0.688–0.893)	< 0.001
Model 3	Reference	0.91 (0.813–1.018)	0.818 (0.726–0.923)	0.791 (0.692–0.905)	< 0.001
Model 4	0.994 (0.991–0.998)				< 0.001

Data are presented as HR (95% CI) unless indicated otherwise. Model 1: Adjusted for age (continuous) and sex (male or female); Model 2: Model 1 plus race/ethnicity, education level, poverty to income ratio, BMI, uric acid, triglycerides, total cholesterol; Model 3: Model 2 plus smoking status, drinking status, diabetes, hypertension, diabetes medicine, hypertension medicine; Model 4: continues model (each per 1% increase in serum concentrations), adjusted by variables in model 3.