Table 1.
Patient characteristics by clopidogrel response.
| Characteristics | All Patients (n = 515) | Responders (n = 268) | Non-Responders (n = 247) | P-Valuea |
|---|---|---|---|---|
| Age (years) | 64.5 ± 11.4 | 64.7 ± 11.2 | 64.3 ± 11.7 | .70 |
| Male, No. (%) | 351 (68.2%) | 194 (72.4%) | 157 (63.6%) | .04 |
| Weight (kg) | 78.4 ± 20.0 | 76.9 ± 18.1 | 80.0 ± 21.8 | .08 |
| Body mass index (kg/m2) | 28.1 ±6.3 | 27.6 ± 5.9 | 28.6 ±6.7 | .09 |
| Body mass index group | .74 | |||
| <18.5 kg/m2 | 16 (3.1%) | 10 (3.7%) | 6 (2.4%) | |
| 18.5–24.9 kg/m2 | 153 (29.8%) | 83 (31.0%) | 70 (28.5%) | |
| 25–29.9 kg/m2 | 180 (35.0%) | 95 (35.4%) | 85 (34.6%) | |
| 30–34.9 kg/m2 | 103 (20.0%) | 52 (19.4%) | 51 (20.7%) | |
| 35–39.9 kg/m2 | 37 (7.2%) | 18 (6.7%) | 19 (7.7%) | |
| ≥40 kg/m2 | 25 (4.9%) | 10 (3.7%) | 15 (6.1%) | |
| Race | .67 | |||
| Black or African American | 161 (31.3%) | 83 (31.0%) | 78 (31.6%) | |
| White | 52 (10.1%) | 31 (11.6%) | 21 (8.5%) | |
| Asian | 64 (12.4%) | 34 (12.7%) | 30 (12.1%) | |
| American Indian or Alaska Native | 4 (0.8%) | 3 (1.1%) | 1 (0.4%) | |
| Native Hawaiian or other Pacific Islander | 1 (0.2%) | 1 (0.4%) | 0 (0.0%) | |
| Unknown | 233 (45.2%) | 116 (43.3%) | 117 (47.4%) | |
| Ethnicity | .72 | |||
| Non-Hispanic | 299 (58.1%) | 156 (58.2%) | 143 (57.9%) | |
| Hispanic | 185 (35.9%) | 98 (36.6%) | 87 (35.2%) | |
| Unknown | 31 (6.0%) | 14 (5.2%) | 17 (6.9%) | |
| History of diabetes | 259 (50.3%) | 128 (47.8%) | 131 (53.0%) | .27 |
| Left heart catheterization indication | .20 | |||
| Acute coronary syndrome | 450 (87.4%) | 229 (85.4%) | 221 (89.5%) | |
| Stable ischemic heart disease | 58 (11.3%) | 35 (13.1%) | 23 (9.3%) | |
| Arrythmia etiology | 4 (0.8%) | 3 (1.1%) | 1 (0.4%) | |
| Staged percutaneous coronary intervention | 1 (0.2%) | 1 (0.4%) | 0 (0.0%) | |
| No left heart catheterization | 2 (0.4%) | 0 (0.0%) | 2 (0.8%) | |
| Intervention type | .29 | |||
| Stent | 467 (90.7%) | 248 (92.5%) | 219 (88.7%) | |
| Median number of stents (n) | 2.0 (1.0–2.0) | 2.0 (1.0–2.0) | 2.0 (1.0–3.0) | |
| Medical management | 27 (5.2%) | 12 (4.5%) | 15 (6.1%) | |
| Other | 21 (4.1%) | 8 (3.0%) | 13 (5.3%) | |
| Clopidogrel responder | 268 (52.0%) | |||
| Adenosine diphosphate (%) | 39.0 (26.0–56.0) | 26.0 (17.0–34.0) | 56.0 (50.0–64.0) | <.001 |