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. Author manuscript; available in PMC: 2022 Dec 19.
Published in final edited form as: Nat Rev Immunol. 2017 Feb 13;17(4):233–247. doi: 10.1038/nri.2017.1
Transcription factor Type of interaction Effects of interaction with glucocorticoid receptor Refs
AP-1 Tethering AP-1 inhibited 124
C/EBPβ Composite C/EBPβ inhibited 125
CREB Composite Enhanced CREB2 activity 126
ETS2 Composite Enhanced ETS2 activity 127
GATA1 Composite GATA1 inhibited 128
NF-κB Tethering NF-κB inhibited 129
NR4A1 Tethering NR4A1 inhibited 130
POU2F1 Tethering POU2F1 inhibited 131
SMAD3 Tethering SMAD3 inhibited 132
STAT3 Tethering Enhanced STAT3 activity 133
STAT5 Tethering Enhanced STAT5 activity 134
STAT6 Tethering STAT6 inhibited 135
T-bet Tethering T-bet inhibited 82

AP-1, activator protein 1; C/EBPβ, CCAAT/enhancer-binding protein-β; CREB, cAMP-responsive element-binding protein; GATA1, GATA-binding factor 1 (also known as erythroid transcription factor); NF-κB, nuclear factor-κB; NR4A1, nuclear receptor subfamily 4 group A member 1 (also known as NUR77); POU2F1, POU domain class 2 transcription factor 1 (also known as OCT1); SMAD3, mothers against decapentaplegic homologue 3; STAT, signal transducer and activator of transcription.