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. 2022 Sep 27;116(6):1842–1851. doi: 10.1093/ajcn/nqac278

FIGURE 2.

FIGURE 2

Kaplan–Meier estimates for risk of KRT initiation and cause-specific Cox regression models according to TMAO and CMPF median groups. Model 1: adjusted for age, sex, eGFR, ACR. Model 2: adjusted as for model 1 plus country, diabetes, preexisting cardiovascular disease, Charlson comorbidity index, diastolic blood pressure, systolic blood pressure, malnutrition (SGA <5). Model 3: adjusted as for model 2 plus albumin, phosphate, hemoglobin. ACR, albumin creatinine ratio; CMPF, 3-carboxy-4-methyl-5-propyl-2-furanpropionate; eGFR, estimated glomerular filtration rate; KRT, kidney replacement therapy; SGA, subjective global assessment; TMAO, trimethylamine N-oxide.