表 1.
APS患者、疾病对照组和健康对照组的临床基本资料
Demographics characteristics of APS patients, disease controls, and healthy controls
| Parameters | APS patients (n=162) | Disease controls (n=122) | Healthy controls (n=50) |
| Data are presented as x±s or n (%). * three classic antibodies in the patient’s serum including the aCL, aβ2GPI, and LAC were all negative during test. APS, antiphospholipid syndrome; CAD, coronary artery disease; aCL, anticardiolipin antibodies; aβ2GPI, anti-β2-glycoprotein Ⅰ anti-bodies; LAC, lupus anticoagulant; aPLs, antiphospholipid antibodies; ox-LDL-Ab, oxidized low-density lipoprotein antibodies. | |||
| Age/years | 41.7±15.2 | 48.8±16.6 | 42.4±10.3 |
| Gender (female) | 143 (88.3) | 106 (86.9) | 33 (66.0) |
| Thrombosis | 98 (60.5) | 0 (0) | 0 (0) |
| Venous thrombosis | 61 (37.7) | 0 (0) | 0 (0) |
| Deep venous thrombosis | 40 (24.7) | 0 (0) | 0 (0) |
| Pulmonary embolism | 19 (11.7) | 0 (0) | 0 (0) |
| Arterial thrombosis | 56 (34.6) | 0 (0) | 0 (0) |
| Cerebral infarction | 35 (21.6) | 0 (0) | 0 (0) |
| CAD | 8 (4.9) | 0 (0) | 0 (0) |
| Atherosclerosis | 47 (29.0) | 0 (0) | 0 (0) |
| Both venous and arterial thrombosis | 19 (11.7) | 0 (0) | 0 (0) |
| Pregnancy morbidity | 78 (48.1) | 0 (0) | 0 (0) |
| Both thrombosis and pregnancy morbidity | 14 (8.6) | 0 (0) | 0 (0) |
| Livedo reticularis | 1 (0.6) | 0 (0) | 0 (0) |
| Thrombocytopenia | 55 (34.0) | 0 (0) | 0 (0) |
| aCL IgG/IgA/IgM (+) | 29 (17.9) | 0 (0) | 0 (0) |
| aβ2GPI IgG/IgA/IgM (+) | 56 (34.6) | 2 (1.6) | 1 (2.0) |
| LAC (+) | 76 (46.9) | 8 (6.6) | 0 (0) |
| Double positive aPLs | 29 (17.9) | 0 (0) | 0 (0) |
| Triple positive aPLs | 34 (21.0) | 0 (0) | 0 (0) |
| Triple negative aPLs* | 42 (25.9) | 111 (91.0) | 49 (98.0) |
| ox-LDL-Ab (+) | 109 (67.3) | 75 (61.5) | 18 (36.0) |