表 2.
APS患者中ox-LDL-Ab与临床症状及实验室指标的关系
The relationship between ox-LDL-Ab and clinical symptoms and laboratory parameters in APS patients
| Parameters | ox-LDL-Ab (+)(n=109), n (%) | ox-LDL-Ab (-)(n=53), n (%) | P value |
| * statistical total population was 142 female patients. # statistical total population was 130 patients. △ statistical total population was 129 patients. LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TCHO, total cholesterol; other abbreviations as in Table 1. Hyper-LDL-C, LDL-C ≥ 4.10 mmol/L; Hypo-HDL-C, HDL-C < 1.03 mmol/L; Hyper-TCHO, TCHO ≥ 6.20 mmol/L; Hypocomplementemia, C3 levels < 0.9 g/L and/or C4 levels < 0.1 g/L. | |||
| Thrombosis | 65 (59.6) | 33 (62.3) | 0.748 |
| Arterial thrombosis | 37 (33.9) | 19 (35.8) | 0.811 |
| Venous thrombosis | 42 (38.5) | 19 (35.8) | 0.741 |
| Pulmonary embolism | 12 (11.0) | 7 (13.2) | 0.683 |
| Cerebral infarction | 22 (20.2) | 13 (24.5) | 0.548 |
| CAD | 5 (4.6) | 3 (5.7) | 0.719 |
| Pregnancy morbidity* | 54 (55.1) | 24 (53.3) | 0.844 |
| Neuropsychiatric symptoms | 8 (7.3) | 7 (13.2) | 0.254 |
| Hyperlipidemia | 36 (33.0) | 14 (26.4) | 0.393 |
| Hyper-LDL-C# | 7 (8.1) | 4 (9.1) | >0.999 |
| Hypo-HDL-C# | 35 (40.2) | 18 (40.9) | 0.940 |
| Hyper-TCHO# | 4 (4.5) | 3 (6.7) | 0.604 |
| aβ2GPI IgG/IgA/IgM (+) | 46 (42.2) | 10 (18.9) | 0.003 |
| aCL IgG/IgA/IgM (+) | 25 (22.9) | 4 (7.5) | 0.017 |
| LAC (+) | 50 (45.9) | 26 (49.1) | 0.703 |
| Thrombocytopenia | 35 (32.1) | 20 (37.7) | 0.478 |
| Hypocomplementemia△ | 36 (42.4) | 20 (45.5) | 0.736 |