表 1.
RA各亚型间临床特点比较
Comparison of clinical characteristics of various subtypes of RA
| Items | Small joint subtype (n=74) | Total joint subtype (n=154) | Systemic subtye (n=100) | Overlapping subtype (n=83) | F/χ2 | P value |
| RA, rheumatoid arthritis; TJC, tender joint counts; SJC, swollen joint counts; DAS28, disease activity score 28-joint count; ESR, erythrocyte sedimentation rate; CRP, C-reaction protein; AID, autoimmune disease. | ||||||
| Female, n (%) | 60 (81.1) | 125 (81.2) | 85 (85.0) | 76 (91.6) | 5.034 | 0.169 |
| Onset Age/years，x±s | 47.04±18.92 | 47.16±13.89 | 44.80±13.56 | 45.10±17.14 | 0.391 | 0.76 |
| Diseae duration /months, x±s | 140.43±103.01 | 142.03±109.38 | 209.80±143.11 | 116.35±111.78 | 1.757 | 0.155 |
| Family history, n (%) | 8 (10.8) | 19 (12.3) | 11 (11.0) | 7 (8.4) | 0.845 | 0.839 |
| History of smoking, n (%) | 12 (16.2) | 26 (16.9) | 15 (15.0) | 10 (12.0) | 1.028 | 0.794 |
| Morning stiffness time＞1 h，n (%) | 44 (61.1) | 70 (47.0) | 56 (57.1) | 45 (58.4) | 5.415 | 0.144 |
| TJC, M (P25, P75) | 3.00 (0.50，16.00) | 6.00 (2.00，14.00) | 14.00 (4.00，23.00) | 8.50 (2.00，18.75) | 27.983 | ＜0.001 |
| SJC, M (P25, P75) | 4.00 (1.50，12.00) | 4.50 (1.75，13.25) | 6.00 (2.00，16.00) | 4.00 (2.00，12.00) | 4.731 | 0.193 |
| DAS28-ESR， M (P25, P75) | 4.30 (3.82，5.82) | 4.95 (4.02，5.92) | 5.41 (4.51，6.95) | 5.07 (3.86，5.99) | 23.880 | ＜0.001 |
| DAS28-CRP， M (P25, P75) | 3.63 (2.79，5.30) | 4.30 (3.32，5.44) | 4.80 (3.67，6.14) | 4.12 (2.99，5.66) | 26.062 | ＜0.001 |
| Small joint involvement, n (%) | 74 (100.0) | 125 (81.2) | 92 (92.0) | 67 (80.7) | 20.929 | ＜0.001 |
| Medium/large joint involvement, n (%) | 0 (0.0) | 154 (100.0) | 100 (100.0) | 61 (73.5) | 320.682 | ＜0.001 |
| Systemic involvement, n (%) | 26 (35.1) | 0 (0.0) | 100 (100.0) | 33 (39.8) | 256.091 | ＜0.001 |
| Other AID overlapped, n (%) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 83 (100.0) | 411.000 | ＜0.001 |