表 3.
抗体阳性和抗体阴性患者的临床特点和实验室特点
Prevalence of symptoms and laboratory abnormalities of SLE patients
| Items | Anti-ENO1(+), n=45 | Anti-ENO1(-), n=37 | P value |
| SLEDAI, systemic lupus erythematosus disease activity index; Tmax, the highest temperature of the patients who had a fever during the disease; anti-dsDNA, anti-double stranded DNA antibody; ANA, antinuclear antibody; anti-U1 RNP, anti-U1 ribonucleoprotein antibody; anti-SSA, anti-Sjögren syndrome A antibody; anti-SSB, anti-Sjögren syndrome B antibody: ESR, erythrocyte sedimentation rate; CRP, C-reactive protein; IgA, immunoglobulin A; IgG, immunoglobulin G; IgM, immunoglobulin M; C3, complement 3; C4, complement 4; WBC, white blood cell count; HB, hemoglobin; PLT, blood platelet count. * P < 0.05, # P < 0.01. | |||
| SLEDAI-2000, x±s | 13.56±6.23 | 11.38±6.20 | 0.119 |
| Fever, n (%) | 26 (57.78) | 31 (83.78) | 0.011* |
| Tmax/℃, x±s | 38.88±0.69 | 38.96±0.79 | 0.705 |
| Rash, n (%) | 19 (42.22) | 17 (45.95) | 0.735 |
| Malar erythema, n (%) | 21 (46.67) | 14 (37.84) | 0.421 |
| Arthralgia, n (%) | 31 (68.89) | 21 (56.76) | 0.256 |
| Hair loss, n (%) | 20 (44.44) | 15 (40.54) | 0.722 |
| Mucosal ulcer, n (%) | 9 (20.00) | 12 (32.43) | 0.199 |
| Photosensitivity, n (%) | 6 (13.33) | 8 (21.62) | 0.301 |
| Raynaud’s phenomenon, n (%) | 9 (20.00) | 7 (18.92) | 0.902 |
| Urine occult blood, n (%) | 9 (20.00) | 15 (40.54) | 0.042* |
| Urine protein, n (%) | 12 (46.67) | 23 (62.16) | 0.161 |
| Pleurisy, n (%) | 14 (31.11) | 10 (27.03) | 0.686 |
| Pericarditis, n (%) | 11 (24.44) | 8 (21.62) | 0.763 |
| Anti-dsDNA (+), n (%) | 21 (47.73) | 12 (32.43) | 0.163 |
| ANA (+), n (%) | 44 (97.78) | 32 (86.49) | 0.127 |
| anti-Sm (+), n (%) | 11 (24.44) | 4 (10.81) | 0.112 |
| anti-U1 RNP (+), n (%) | 19 (42.22) | 10 (27.03) | 0.152 |
| anti-SSA (+), n (%) | 21 (46.67) | 17 (45.95) | 0.948 |
| anti-SSB (+), n (%) | 6 (13.33) | 0 | 0.060 |
| ESR/(mm/h), M (range) | 29.50 (1.52－110.00) | 12.00 (4.00－101.00) | 0.001# |
| CRP/(mg/L), M (range) | 1.30 (0.30－52.40) | 1.55 (0.39－101.71) | 0.922 |
| IgA/(g/L), M (range) | 2.85 (0.07－27.00) | 2.05 (0.42－4.36) | 0.014* |
| IgG/(g/L), M (range) | 14.30 (4.02－37.80) | 10.46 (2.50－25.73) | 0.0003# |
| IgM/(g/L), M (range) | 0.90 (0.22－3.18) | 0.69 (0.17－2.24) | 0.148 |
| C3/(g/L), x±s | 0.63±0.31 | 0.73±0.29 | 0.157 |
| C4/(g/L), M (range) | 0.14 (0.02－0.47) | 0.16 (0.02－0.49) | 0.245 |
| WBC/(×109 /L), M (range) | 6.40 (1.89－12.20) | 5.00 (1.50－17.60) | 0.132 |
| HB/(g/L), x±s | 107.98±19.09 | 111.32±23.76 | 0.481 |
| PLT/(×109 /L), x±s | 205.87±67.98 | 164.57±69.57 | 0.008# |