Fig. 3.

Identification of proteins that strongly differentiate FSA tumor tissue from all three surrounding PTTs. A) Proteins highly overexpressed in tumor tissue compared to all three PTTs (log2 fold-change ≥ 2, p-value < 0.05). N/A = not applicable, as protein was not detected in the respective tissue type. B) Representative image of immunohistochemical staining for Tenascin-C in a case of FSA (case #11). Tumor tissue is strongly staining, while staining in AT and CT is negligible or absent. C) Venn diagram showing all detected proteins per tissue type. 113 proteins were uniquely detected in tumor tissue. D) Representative image of immunohistochemical staining for Iba-1 in a case of FSA (case #19). Tumor tissue is strongly staining, while staining in AT and CT is negligible or absent.