Table 1.
List of mass spectrometric features (m/z values) with nonzero t-statistic versus those in the mean MALDI-MSI spectrum in each segment by Spatial Shrunken Centroids method of Cardinal MSI on the MALDI-MSI data of tumoral brain section. See text for details on the interpretation of t-statistic value.
| Normal brain parenchyma |
Tumoral brain parenchyma |
||||||
|---|---|---|---|---|---|---|---|
| m/z | t-Statistic | m/z | t-Statistic | m/z | t-Statistic | m/z | t-Statistic |
| Segment 1 | Segment 2 | ||||||
| 788.62 | 31.745 | 784.60 | −0.960 | 810.60 | 91.157 | 731.61 | −0.110 |
| 760.59 | 15.208 | 782.57 | −3.761 | 782.57 | 75.747 | 651.58 | −1.020 |
| 762.60 | 12.623 | 736.56 | −4.578 | 808.59 | 6.496 | 736.56 | −1.610 |
| 706.54 | −10.543 | 784.60 | 3.986 | 788.62 | −2.398 | ||
| 758.57 | −11.872 | 627.54 | 3.027 | 732.55 | −3.855 | ||
| 732.55 | −16.906 | 760.59 | −6.238 | ||||
| 786.60 | −17.281 | 734.57 | −8.649 | ||||
| 734.57 | −18.160 | 762.60 | −12.453 | ||||
| Segment 3 | Segment 4 | ||||||
| 762.60 | 17.405 | 496.34 | −2.339 | 666.64 | 95.932 | 651.58 | −0.540 |
| 734.57 | 8.669 | 784.60 | −4.452 | 638.61 | 70.556 | 782.57 | −0.650 |
| 731.61 | 4.855 | 706.54 | −19.773 | 610.58 | 59.721 | 810.60 | −0.950 |
| 651.58 | 2.887 | 758.57 | −22.169 | 650.64 | 51.093 | 736.56 | −2.482 |
| 736.56 | 1.610 | 732.55 | −31.981 | 788.60 | −5.264 | ||
| 786.60 | −39.440 | 762.60 | −16.122 | ||||
| 760.59 | −26.966 | ||||||
| 734.57 | −27.085 | ||||||
| Segment 5 | Segment 7 | ||||||
| 788.62 | 32.874 | 732.55 | −0.820 | 786.60 | 128.083 | 806.57 | −5.314 |
| 760.59 | 2.113 | 734.57 | −13.643 | 732.55 | 100.544 | 731.61 | −9.345 |
| 706.54 | 71.320 | 651.58 | −11.777 | ||||
| 758.57 | 49.195 | 810.60 | −14.988 | ||||
| 760.59 | 9.627 | 782.57 | −16.111 | ||||
| 784.60 | 7.225 | 736.56 | −16.999 | ||||
| 788.62 | 6.902 | 762.60 | −33.280 | ||||
| 496.34 | 3.988 | 734.57 | −57.408 | ||||
| 605.56 | 2.921 | ||||||
| Segment 6 | Segment 8 | ||||||
| 788.60 | 62.251 | 806.57 | −0.710 | 732.55 | 16.312 | 651.58 | −5.829 |
| 605.56 | 12.262 | 651.58 | −1.850 | 798.64 | 15.342 | 731.61 | −5.934 |
| 760.59 | 3.381 | 706.54 | −3.219 | 786.60 | 15.323 | 736.56 | −7.968 |
| 758.57 | −3.595 | 496.34 | 14.221 | 762.60 | −9.963 | ||
| 731.61 | −3.828 | 782.57 | 14.114 | 734.57 | −20.532 | ||
| 732.55 | −7.063 | 760.59 | 12.058 | ||||
| 736.56 | −8.021 | 758.57 | 7.250 | ||||
| 734.57 | −31.684 | 808.57 | 3.626 | ||||
| 772.62 | 3.243 | ||||||
| 806.57 | 2.847 | ||||||
| 810.60 | 2.400 | ||||||
| 788.62 | 0.450 | ||||||
| 784.60 | 0.440 | ||||||
| Segment 10 | Segment 9 | ||||||
| 734.57 | 88.693 | 638.61 | −0.720 | 786.60 | 97.386 | 806.57 | −1.690 |
| 736.56 | 31.095 | 605.56 | −2.111 | 732.55 | 93.210 | 810.57 | −7.780 |
| 762.60 | 25.661 | 666.64 | −2.669 | 758.57 | 83.100 | 788.62 | −7.914 |
| 651.58 | 18.341 | 810.60 | −2.741 | 706.59 | 61.876 | 731.61 | −12.648 |
| 731.61 | 11.231 | 798.64 | −4.436 | 784.60 | 28.012 | 651.58 | −15.502 |
| 806.57 | 0.680 | 496.34 | −9.294 | 496.34 | 15.878 | 736.56 | −16.418 |
| 784.60 | −10.397 | 798.64 | 12.049 | 762.60 | −43.317 | ||
| 760.59 | −25.077 | 760.59 | 7.426 | 734.57 | −43.529 | ||
| 706.54 | −34.743 | 772.62 | 1.170 | ||||
| 758.57 | −39.382 | ||||||
| 788.62 | −47.395 | ||||||
| 732.55 | −57.759 | ||||||
| 786.60 | −71.654 | ||||||