Table 2.
The risk of bias of studies
| Outcomes | Heterogeneity (I2), P-value | Harbord’s test | Egger’s test | number of studies |
|---|---|---|---|---|
| Mortality | 48%, 0.04 | 0.4865 | 0.4832 | 10 |
| severe TBI (GCS 3 to 8) | 0%, 0.79 | 0.3983 | 0.3346 | 4 |
| GOS < 4 | 71%, 0.004 | 0.5533 | 0.5925 | 6 |
| Neurosurgical Intervention | 0%, 0.73 | 0.3403 | 0.3356 | 5 |
| Rebleeding | 0%, 0.73 | 0.5421 | 0.5066 | 4 |
| adverse eventa | 50%, 0.08 | 0.1543 | 0.2468 | 6 |
| Vascular occlusive events | 0%, 0.37 | 0.8878 | 0.9214 | 3 |
| Pulmonary embolism | 64%, 0.06 | 0.2980 | 0.7334 | 4 |
| Deep vein thrombosis | 0%, 0.60 | 0.6228 | 0.8206 | 4 |
| Neurological complications | 27%, 0.25 | 0.0328 | 0.0682 | 4 |
TBI Traumatic brain injury, GCS Glasgow coma scale, GOS Glasgow outcome scale
aindicates Vascular occlusive events + Pulmonary embolism + Deep vein thrombosis + Neurological complications