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. 2022 Dec 5;13:1052736. doi: 10.3389/fendo.2022.1052736

Table 1.

Participant characteristics of CKD and non-CKD populations.

Total (n = 8866) Men (n = 3117) Women (n = 5749)
eGFR ≥60 (n=8707) eGFR<60 (n=159) P value eGFR ≥60 (n=3056) eGFR<60 (n=61) P value eGFR ≥60 (n=5651) eGFR<60 (n=98) P value
Age (years) 60.46 ± 10.04 68.32 ± 10.08 <0.001 62.42 ± 9.80 68.05 ± 8.33 <0.001 59.40 ± 10.00 68.49 ± 11.06 <0.001
Current smoker (%) 13.9 9.4 0.105 38.4 23.0 0.014 0.7 1.0 0.490
Current drinker (%) 12.5 3.1 <0.001 33.1 6.6 <0.001 1.4 1.0 0.999
Physically active (%) 62.9 55.3 0.051 61.8 54.1 0.218 63.5 56.1 0.135
FPG (mmol/L) 5.53 ± 1.28 5.84 ± 2.02 0.059 5.53 ± 1.10 5.68 ± 1.34 0.301 5.53 ± 1.37 5.93 ± 2.34 0.092
2-h PG (mmol/L) 6.92 ± 5.02 7.83 ± 3.65 0.023 6.69 ± 2.59 7.45 ± 3.29 0.024 7.04 ± 5.93 8.07 ± 3.86 0.089
HbA1c (%) 5.81 ± 0.87 6.01 ± 1.03 0.004 5.73 ± 0.68 5.90 ± 0.94 0.051 5.85 ± 0.95 6.07 ± 1.08 0.023
TGs (mmol/L) 1.23 (0.89-1.77) 1.39 (1.02-1.92) 0.005 1.10 (0.81-1.64) 1.16 (0.96-1.58) 0.254 1.30 (0.95-1.82) 1.51 (1.16-2.12) 0.002
HDL-C (mmol/L) 1.50 ± 0.36 1.41 ± 0.33 0.002 1.52 ± 0.40 1.41 ± 0.31 0.044 1.50 ± 0.33 1.42 ± 0.34 0.016
SBP (mmHg) 150.62 ± 23.83 157.97 ± 26.37 <0.001 152.82 ± 23.51 155.93 ± 24.47 0.307 149.44 ± 23.92 159.23 ± 27.53 0.001
DBP (mmHg) 81.68 ± 12.40 82.45 ± 15.52 0.533 82.82 ± 13.38 84.36 ± 17.73 0.503 81.05 ± 11.79 81.26 ± 13.94 0.886
Hypertension (%) 68.1 81.8 <0.001 72.2 82.0 0.092 65.9 81.6 0.001
Diabetes (%) 12.5 19.5 0.009 12.0 16.4 0.294 12.8 21.4 0.012
CVD (%) 7.3 11.9 0.027 8.4 19.7 0.002 6.7 7.1 0.875
METS-VF 6.40 ± 0.59 6.66 ± 0.53 <0.001 6.52 ± 0.58 6.75 ± 0.55 0.001 6.34 ± 0.58 6.60 ± 0.51 <0.001
LAP 24.32 (13.92-41.60) 29.83 (17.02-53.60) 0.002 18.25 (9.90-32.76) 22.25 (12.32-33.91) 0.129 27.96 (16.68-46.00) 37.92 (21.54-59.55) 0.001
VAI 1.38 (0.86-2.25) 1.61 (1.00-2.70) 0.003 0.93 (0.61-1.58) 1.18 (0.74-1.54) 0.099 1.63 (1.08-2.55) 2.16 (1.41-3.27) <0.001
ABSI 0.078 ± 0.007 0.081 ± 0.007 <0.001 0.078 ± 0.007 0.079 ± 0.005 0.237 0.078 ± 0.007 0.081 ± 0.007 <0.001
BRI 3.65 ± 1.17 4.04 ± 1.24 <0.001 3.40 ± 1.03 3.73 ± 1.03 0.012 3.79 ± 1.21 4.24 ± 1.33 <0.001
CMI 0.97 (0.63-1.59) 1.22 (0.73-1.95) <0.001 0.86 (0.54-1.47) 1.07 (0.68-1.54) 0.058 1.04 (0.68-1.65) 1.39 (0.91-2.09) <0.001
WHtR 0.51 ± 0.06 0.53 ± 0.06 <0.001 0.50 ± 0.05 0.52 ± 0.05 0.01 0.52 ± 0.06 0.54 ± 0.06 <0.001
WC (cm) 81.15 ± 9.20 83.47 ± 9.33 0.002 82.32 ± 9.07 84.18 ± 8.53 0.112 80.51 ± 9.21 83.03 ± 9.80 0.007
BMI (kg/m2) 23.70 ± 3.09 23.86 ± 3.34 0.527 23.43 ± 2.99 24.01 ± 3.25 0.137 23.85 ± 3.13 23.77 ± 3.41 0.798

Continuous variables are expressed as the means (standard deviations) or medians (IQRs), and categorical variables are expressed as numbers (percentages). 2-h PG, 2-hour postprandial blood glucose; TGs, triglycerides; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; SBP, systolic blood pressure; DBP, diastolic blood pressure; CVD, cardiovascular disease; METS-VF, metabolic score for visceral fat; LAP, lipid accumulation product; VAI, visceral adiposity index; ABSI, a body shape index; BRI, body roundness index; CMI, cardiometabolic index; WHtR, waist-to-height ratio; WC, waist circumference; BMI, body mass index.