Table 7.
Combined intake of estragole and dillapiole and combined margin of exposure (MOET) calculated at the maximum proposed use level of the additive in feed (15 mg/kg complete feed)
| Animal category | Daily feed intake | Body weight | Use level in feed | Estragole+ diallapiole (a) intake | MOET (b) |
|---|---|---|---|---|---|
| kg DM/day | kg | mg/kg feed | μg/kg bw per day | ||
| Chicken for fattening | 0.158 | 2 | 15 | 1.158 | 19,170 |
| Laying hen | 0.106 | 2 | 15 | 0.777 | 28,574 |
| Turkey for fattening | 0.176 | 3 | 15 | 0.860 | 25,814 |
| Piglet | 0.88 | 20 | 15 | 0.645 | 34,419 |
| Pig for fattening | 2.2 | 60 | 15 | 0.538 | 41,302 |
| Sow lactating | 5.28 | 175 | 15 | 0.442 | 50,194 |
| Veal calf (milk replacer) | 1.89 | 100 | 15 | 0.258 | 86,047 |
| Cattle for fattening | 8 | 400 | 15 | 0.293 | 75,721 |
| Dairy cow | 20 | 650 | 15 | 0.451 | 49,219 |
| Sheep/goat | 1.2 | 60 | 15 | 0.293 | 75,721 |
| Horse | 8 | 400 | 15 | 0.293 | 75,721 |
| Rabbit | 0.1 | 2 | 15 | 0.733 | 30,288 |
| Salmon | 0.0021 | 0.12 | 15 | 0.257 | 86,538 |
| Dog | 0.25 | 15 | 15 | 0.244 | 90,865 |
| Cat | 0.06 | 3 | 15 | 0.293 | 75,721 |
| Ornamental fish | 0.00054 | 0.012 | 15 | 0.066 | 336,537 |
DM: dry matter; bw: body weight.
(a)
The intake values of estragole and dillapiole are calculated considering the highest analysed value in the additive for both compounds.
(b)
The MOE for estragole is calculated as the ratio of the reference point (BMDL10) to the intake.