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. Author manuscript; available in PMC: 2023 Feb 1.
Published in final edited form as: Am J Psychiatry. 2022 Mar 25;179(8):562–572. doi: 10.1176/appi.ajp.21090896

FIGURE 1.

FIGURE 1.

Cognitive ability from 6 to 24 months in infants at high or low likelihood for ASD who did or did not develop ASD and infants with fragile X syndromea

a ASD=autism spectrum disorder; FXS=fragile X syndrome; HL-ASD=infants at high likelihood for ASD who were later diagnosed with ASD; HL-negative=high-likelihood infants who were negative for ASD; LL-negative=low-likelihood infants who were negative for ASD. Compared with all other groups, the infants with fragile X syndrome had significantly lower cognitive ability (Mullen Early Learning composite score) starting at 6 months of age and remaining significantly lower at 12 and 24 months. The HL-ASD group showed no differences in cognitive ability at6 months relative to HL- and LL-negative control infants but showed significantly lower cognitive ability by 12 months of age. Error bars indicate standard error of the mean.