Table 4.
Brainstem white matter regions of interest and sensory response patterns in the autistic group
| Brainstem white matter region | Hyporesponsiveness | Hyperresponsiveness | Enhanced perception | Sensory seeking | ||||
|---|---|---|---|---|---|---|---|---|
| FWE-FA | FWE-MD | FWE-FA | FWE-MD | FWE-FA | FWE-MD | FWE-FA | FWE-MD | |
| r | r | r | r | r | r | r | r | |
| CST | .30 a | − .22 | .06 | − .11 | − .08 | − .05 | .06 | − .14 |
| ML | .23 | − .41 a,b | .09 | − .25 | .07 | − .20 | .23 | − .15 |
| LL | .18 | − .49 a,b | .08 | − .21 | .15 | − .21 | .20 | − .33a |
| FPT | .12 | − .04 | − .17 | − .09 | − .11 | − .06 | .08 | − .13 |
| POTPT | .15 | − .30 a,b | − .03 | − .19 | − .05 | − .23 | − .07 | − .29 a |
| STT | .10 | − .42 a,b | .07 | − .25 | < .001 | − .25 | .17 | − .19 |
| SCPCT | .20 | − .42 a,b | .07 | − .12 | − .01 | − .11 | .18 | − .17 |
| SCPSC | .02 | − .28 a,b | − .08 | − .07 | − .11 | − .03 | .06 | − .09 |
| ICPMC | .18 | − .35 a,b | .06 | − .24 | .14 | − .20 | .08 | − .21 |
| ICPVC | .16 | − .35 a,b | .11 | − .23 | .14 | − .20 | .09 | − .22 |
| MCP | .39 a,b | − .30 a,b | .37a | − .21 | .25 | − .18 | .27 a | − .20 |
Partial correlations account for age, sex and average head motion during DWI brain scan
CST Corticospinal tract, ML Medial lemniscus, LL Lateral lemniscus, STT Spinothalamic tract, SCPCT Superior cerebellar peduncle cerebellothalamic tract, SCPSC Superior cerebellar peduncle spinocerebellar tract, MCP Middle cerebellar peduncle, ICPMC Inferior cerebellar peduncle tracts from medulla oblongata to the cerebellum, ICPVCT Inferior cerebellar peduncle vestibulocerebellar tract, FPT Frontopontine tract, POTPT Parieto-occipito-temporo-pontine tract
aUncorrected p < .05
bFalse discovery rate corrected (FDR) p < .05