Table 3.
Univariable and multivariable Cox proportional hazards model for sustained VA prediction
| Univariable model | Multivariable model 1 | Multivariable model 2 | Multivariable model 3 | |||||
|---|---|---|---|---|---|---|---|---|
| RVEF | LVEF | ARVC VA risk calculator | ||||||
| HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Right ventricular strain | ||||||||
| GLS | 1.05 (1.00–1.11) | 0.053 | ||||||
| Basal region | 1.06 (1.02–1.11) | 0.015 | 1.03 (0.98–1.08) | 0.238 | 1.06 (1.01–1.10) | 0.099 | 1.05 (1.00–1.10) | 0.107 |
| Mid region | 1.05 (1.01–1.10) | 0.037 | 1.02 (0.98–1.07) | 0.312 | 1.04 (1.00–1.09) | 0.099 | 1.03 (0.98–1.08) | 0.240 |
| Apical region | 1.03 (1.00–1.07) | 0.097 | ||||||
| Left ventricular strain | ||||||||
| GCS | 1.22 (1.07–1.39) | 0.015 | 1.17 (1.02–1.35) | 0.054 | 1.18 (0.99–1.42) | 0.099 | 1.18 (1.02–1.35) | 0.107 |
| Anterior region | 1.12 (1.01–1.24) | 0.047 | 1.10 (0.99–1.23) | 0.105 | 1.08 (0.97–1.21) | 0.152 | 1.10 (0.98–1.23) | 0.177 |
| Anterolateral region | 1.12 (1.03–1.23) | 0.015 | 1.10 (1.00–1.20) | 0.081 | 1.09 (0.99–1.20) | 0.116 | 1.09 (1.00–1.19) | 0.118 |
| Posterolateral region | 1.15 (1.04–1.26) | 0.020 | 1.12 (1.02–1.24) | 0.054 | 1.11 (1.00–1.23) | 0.099 | 1.10 (1.00–1.22) | 0.110 |
| Inferior region | 1.09 (1.00–1.19) | 0.053 | ||||||
| Septal region | 1.18 (1.07–1.31) | 0.015 | 1.16 (1.02–1.32) | 0.054 | 1.15 (0.99–1.32) | 0.099 | 1.17 (1.02–1.33) | 0.107 |
GCS, global circumferential strain; GLS, global longitudinal strain; LVEF, left ventricular ejection fraction; RVEF, right ventricular ejection fraction. False discovery rate corrected P-values are given in this table. Boldface values are statistically significant (p ≤ 0.05).