Table 1.
Baseline clinical characteristics
| All patients (n = 566) | LARS ≤22% (n = 277) | LARS >22% (n = 289) | P-value | |
|---|---|---|---|---|
| Age (years) | 63.6 ± 12.3 | 67.3 ± 10.6 | 60.1 ± 12.9 | <0.001 |
| Male sex (%) | 375 (66.3%) | 176 (63.5%) | 199 (68.9%) | 0.184 |
| Heart rate (bpm) | 75 ± 20 | 80 ± 20 | 71 ± 18 | <0.001 |
| Systolic BP (mmHg) | 135 ± 19 | 134 ± 20 | 136 ± 19 | 0.308 |
| Diastolic BP (mmHg) | 77 ± 11 | 77 ± 11 | 77 ± 11 | 0.961 |
| BMI (kg/m2) | 24.9 ± 3.4 | 25.1 ± 3.5 | 24.8 ± 3.4 | 0.348 |
| Hypertension (%) | 231 (40.8%) | 112 (40.4%) | 119 (41.2%) | 0.865 |
| Diabetes mellitus (%) | 16 (2.8%) | 8 (2.9%) | 8 (2.8%) | 1.000 |
| Smoker (%) | 186 (36.5%) | 93 (37.5%) | 93 (35.5%) | 0.647 |
| Coronary artery disease (%) | 127 (23.1%) | 71 (26.3%) | 56 (20.0%) | 0.086 |
| COPD (%) | 37 (6.7%) | 23 (8.5%) | 14 (5.0%) | 0.125 |
| eGFR (mL/min/1.73 m2) | 79.9 ± 24.9 | 73.6 ± 23.1 | 86.0 ± 25.1 | <0.001 |
| CKD, eGFR < 60 mL/min/1.73 m2 (%) | 116 (20.6%) | 81 (29.2%) | 35 (12.2%) | <0.001 |
| Atrial fibrillation (%) | 188 (33.2%) | 144 (52.0%) | 44 (15.2%) | <0.001 |
| NYHA class ≥III (%) | 120 (21.2%) | 83 (30.0%) | 37 (12.8%) | <0.001 |
Values in boldface are considered statistically significant (p-value <0.05). BMI, body mass index; BP, blood pressure; CKD, chronic kidney disease; COPD, chronic obstructive pulmonary disease; eGFR, estimated glomerular filtration rate; LARS, left atrial reservoir strain; NYHA, New York Heart Association.