Table 2.
Baseline echocardiographic characteristics
| All patients (n = 566) | LARS ≤22% (n = 277) | LARS >22% (n = 289) | P-value | |
|---|---|---|---|---|
| LVEDD (mm) | 54.5 ± 6.5 | 54.6 ± 6.5 | 54.3 ± 6.5 | 0.563 |
| LVESD (mm) | 33.1 ± 6.8 | 34.0 ± 6.8 | 32.3 ± 6.7 | 0.002 |
| LVEDV index (mL/m2) | 71 ± 19 | 70 ± 21 | 72 ± 18 | 0.290 |
| LVESV index (mL/m2) | 24 (19–31) | 24 (19–31) | 24 (19–30) | 0.415 |
| LVEF (%) | 64 ± 8 | 63 ± 9 | 66 ± 7 | <0.001 |
| LV GLS (%) | 21.4 ± 4.0 | 19.9 ± 4.1 | 22.8 ± 3.3 | <0.001 |
| E/e′ | 12 (9–16) | 13 (10–18) | 11 (9–15) | 0.002 |
| sPAP (mmHg) | 32 (25–42) | 35 (29–48) | 29 (25–35) | <0.001 |
| EROA (cm2) | 41 (29–54) | 42 (31–55) | 39 (29–53) | 0.048 |
| RVol (mL) | 55 ± 23 | 57 ± 22 | 53 ± 24 | 0.064 |
| Vena contracta (mm) | 7.2 ± 1.7 | 7.5 ± 1.7 | 6.9 ± 1.7 | <0.001 |
| LAVi (mL/m2) | 50 (39–67) | 61 (45–84) | 45 (35–54) | <0.001 |
| LARS (%) | 23.0 ± 9.7 | 15.3 ± 4.5 | 30.5 ± 6.9 | <0.001 |
Values in boldface are considered statistically significant (p-value <0.05). EDD, end-diastolic diameter; EDV, end-diastolic volume; EF, ejection fraction; EROA, effective regurgitant orifice area; ESD, end-systolic diameter; ESV, end-systolic volume; GLS, global longitudinal strain; LARS, left atrial reservoir strain; LAVi, left atrial volume index; LV, left ventricular; RVol, regurgitant volume; sPAP, systolic pulmonary artery pressure.