Table 1.

Overview of bioinformatic evidence for genes prioritized and taken forward for downstream functional analysis

Gene	ColB	ColG	Protein–protein interaction	GWAS	MPD	MLS
ATP13A2					X	X
CCNT2				X
CD38	X	X		X
CTSB	X	X	X
DDRGK1				X
DGKQ				X
DJ1					X
DNAJC13					X
FBXO7					X
GALC	X			X		X
GBA			X		X	X
GPNMB	X	X		X
HSD3B7		X
IDUA						X
INPP5F			X
KAT8		X	X	X
KLHL7		X		X
LRRK2			X	X	X
LSM7	X	X		X
MAPT			X	X
NCKIPSD	X	X	X	X
NEK1	X
NSF			X
NUCKS1		X		X
NUPL2	X	X		X
PDLIM2		X		X
PM20D1	X
PRKN					X
RAB7L1	X	X	X
SH3GL2			X
SLC41A1		X		X
SNCA					X
SPPL2B	X
STK39				X
VAMP4	X	X
VPS35					X
WDR6	X	X
ZNF646				X

ColB = coloc analysis using Braineac; ColG = coloc analysis using genotype-tissue expression; GWAS = genes prioritized in Parkinson’s disease GWAS³; MLS = Mendelian genes associated with lysosomal storage disorders; MPD = Mendelian genes associated with Parkinson’s disease; WPPINA = weighted protein interaction network.