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. 2022 Dec 20;6:81. doi: 10.1186/s41927-022-00313-8

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Kidney Biopsy showing a light microscopy, b immunofluorescence and c electron microscopy. a By light microscopy, glomeruli had a mild increase in mesangial matrix and cells with intact appearing basement membranes. The interstitium, tubules, and small vessels were normal except for abundant protein droplets the tubular epithelium. b Granular mesangial and peripheral staining was present on direct antibody immunofluorescence with antibodies against IgA, IgG, IgM, C3, and C1q. c Ultrastructural examination confirmed abundant mesangial and paramesangial deposits. Numerous early subepithelial membranous deposits were associated with small basement membrane spikes. Subendothelial tubuloreticular bodies were present (not shown)