Table 1.
Modifiable | Non-modifiable | |
---|---|---|
CLABSI [12, 41] |
Prolonged hospitalization before central-line placement Total parenteral nutrition Extracorporeal life support Renal replacement therapy Multilumen catheters Type of CVC material Site and insertion techniques - handling Duration of indwelling catheter |
Young age (especially newborn) Male gender Burns Genetic abnormality Immune deficiency |
VAP [42] |
Reintubation/Self-extubation Prolonged mechanical ventilation Supine position Previous antibiotic uses and bloodstream infection Use of steroids Use of gastric acid–modifying drugs Use of narcotics, neuromuscular agents Invasive procedures like bronchoscopy |
Genetic syndrome Neurological impairment Immunodeficiency Airway malformations Congenital heart disease |
CAUTI [20] |
Duration of catheterization Breach in catheter sterility Chronic undernutrition |
Chronic kidney disease Immune deficiency Fecal incontinence |
CAUTI Catheter-associated urinary tract infection, CLABSI Central line–associated blood stream infection, CVC Central venous catheter, HAI Health care–associated infections, VAP Ventilator-associated pneumonia