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. 2019 Jul 29;54(12):2051–2059. doi: 10.1038/s41409-019-0629-7

Table 4.

Multivariate analysis of factors affecting on survival outcomes

Progression-free survival Overall survival
HR (95% CI) P-value HR (95% CI) P-value
Age 0.95 (0.92–0.99) 0.012
LDH > normal 3.01 (.38–6.58) <0.001
β2 microglobulin ≥ 5.5 mg/L 2.91 (1.68–5.02) <0.001
Pre-ASCT
 CR 1
 VGPR 3.14 (1.20–8.21) 0.05
 PR 5.96 (1.93–18.39) 0.009
Post-ASCT at 3 months
 CR 1 1
 VGPR 1.24 (0.68–2.25) 0.557 4.21 (1.71–10.37) 0.009
 PR 1.97 (0.86–4.54) 0.179 2.15 (0.56–8.24) 0.35
 PD 53.2 (15.8–178.9) <0.001 23.7 (7.13–78.75) <0.001

HR hazard ratio, CI confidence interval, LDH lactate dehydrogenase, CR complete response, VGPR very good partial response, PR partial response, PD progressive disease