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. 2022 Mar 31;72(1):153–167. doi: 10.1136/gutjnl-2021-325915

Table 1.

Patient information

Group Immune tolerant Immune activation AR CR HC
Cases 6 5 3 3 6
Age (years) 34 (21–55) 29 (25–45) 37 (28–45) 47 (45–49) 52 (33–66)
Sex (M/F) 4/2 4/1 2/1 3/0 4/2
Time since HBV diagnosis (years) 14.7 (1.5–27.0) 20 (10–20) <0.5 10 (1–20) NA
HBsAg level (IU/mL) 40 636 (5652–69 050) 7881 (833.2–32 970.0) 783 (0–1293) <0.05 NA
HBV DNA level (log10 IU/mL) 8.328 (8–8.88) 6.761 (5.29–8) 0.9783 (0–2.935) LDL NA
ALT (U/L) 36.1 (20–45.7) 232.2 (60–424) 108 (25–192) 18.67 (13–22) 20.8 (11–31)
AST (U/L) 28.7 (19–42) 91.2 (34–129) 44 (21–58) 19 (16–24) 19 (15–27)

ALT, alanine aminotransferase; AR, acute recovery; AST, aspartate transaminase; CR, chronic resolved; F, female; HBsAg, HBV surface antigen; HC, healthy control; LDL, lower detection limit; M, male; NA, not applicable.