TABLE 3.

Logistic regression analysis of clinical characteristics associated with the presence of ILD in SSc*.

Variables	Univariable analysis		Multivariable analysis
	Odds ratio (95% CI)	P-value	Odds ratio (95% CI)	P-value
Loss of finger pad	1.911(1.004−3.636)	0.049
Sclerodactyly	1.750(1.029−2.977)	0.039
Muscle involvement	2.375(1.078−5.233)	0.032	2.551(1.054−6.175)	0.038
LVDD	2.054(1.208−3.490)	0.008	2.360(1.277−4.361)	0.006
PAH	5.612(1.596−19.731)	0.007	9.134(2.335−35.730)	0.001
dcSSc	2.754(1.543−4.914)	0.001	2.859(1.489−5.487)	0.002
NLR	1.155(1.017−1.312)	0.027
PLR	1.005(1.001−1.008)	0.008	1.005(1.001−1.008)	0.020
Elevated ferritin	2.371(1.207−4.656)	0.012
Elevated KL-6	2.103(1.227−3.604)	0.007	2.033(1.099−3.763)	0.024
Anti-Scl-70	2.129(1.232−3.679)	0.007	3.101(1.647−5.840)	< 0.001
ACA	0.476(0.259−0.875)	0.017

*All variables with a p-value below 0.05 from the univariable analysis were entered in multivariable analysis (forward logistic regression). SSc, systemic sclerosis; ILD, interstitial lung disease; LVDD, left ventricular diastolic dysfunction; dcSSc, diffuse cutaneous systemic sclerosis; NLR, neutrophil to lymphocyte ratio; PLR, platelet to lymphocyte ratio; KL-6, Krebs von den Lungen-6; anti-Scl-70, anti-scleroderma-70; ACA, anti-centromere antibody. Bold values indicate P < 0.05.