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. 2022 Dec 19;12:21886. doi: 10.1038/s41598-022-26094-1

Table 2.

Amount of drug loaded per mL of DC Bead LUMI.

Drug Doxorubicin HCl* Gardiquimod DSR 6434 Imiquimod BMS-202
Maximum drug loaded, mg drug/ml beads 204.54 ± 3.87 65.97 ± 1.54 65.95 ± 6.96 65.28 ± 3.09 148.05 ± 2.24
mM drug/ml beads equivalent of drug loaded to sulfonated bead 0.35 ± 0.01 0.21 ± 0.00 0.16 ± 0.02 0.27 ± 0.01 0.35 ± 0.01
Theoretical maximum loading level based on SO3 contents (mg) 166.5 89.95 114.94 68.97 120.4
Drug: sulfonate 1.228 0.733 0.574 0.946 1.223

*Maximum loading reflects the amount of each drug in its basic form except for Dox which is available in its salt form.