Table 2.
Variables associated with the SAF category: No NAFLD, NAFLD without NASH and NASH (n = 155).
| Variable | No NAFLD (n = 83) | NAFLD no NASH (n = 44) | NASH (n = 28) | p |
|---|---|---|---|---|
| Age, years | 59 (44–70) | 61 (54–71) | 66 (54–71) | 0.099 |
| Female sex, n (%) | 52 (63) | 26 (59) | 19 (68) | 0.755 |
| BMI, Kg/m2† | 26.9 (24–29) | 28.9 (25–33) | 30.7 (27–35) | 0.004 |
| T2DM, n (%) | 9 (11) | 4 (9) | 17 (61) | < 0.001 |
| FPG ≥ 100 mg/dL, n (%) | 22 (27) | 23 (52) | 22 (79) | < 0.001 |
| FPG, mg/dL† | 91 (85–101) | 101 (92–107) | 112 (101–135) | < 0.001 |
| HOMA† | 1.8 (1.1–2.98) | 2.9 (1.9–3.3) | 5.6 (3.9–9.0) | < 0.001 |
| Triglycerides, mg/dL† | 98 (67–118) | 110 (83–153) | 132 (95–218) | 0.001 |
| Cholesterol, mg/dL† | 189 (164–214) | 194 (187–236) | 191 (173–233) | 0.138 |
| HDL-c, mg/dL† | 53 (43–65) | 48 (40–64) | 45 (35–57) | 0.009 |
| Metabolic syndrome, n (%) | 50 (52) | 36 (78) | 23 (82) | 0.001 |
| ALT, IU/mL† | 16 (13–25) | 21 (15–27) | 22 (17–34) | 0.018 |
| AST, IU/mL† | 27 (15–23) | 19 (16–22) | 20 (16–26) | 0.220 |
| GGT, IU/mL† | 27 (17–65) | 34 (26–88) | 48 (31–82) | 0.001 |
| Liver stiffness, kPa† | 4.6 (3.8–6.3) | 5.6 (4.3–6.5) | 7.0 (4.9–11.7) | < 0.001 |
| CAP, dB/m† | 239 (204–268) | 287 (263–322) | 337 (279–365) | < 0.001 |
CAP controlled attenuation parameter, BMI Body mass index, HDL-c HDL-cholesterol, HOMA homeostasis model assessment, FPG Fasting plasma glucose, T2DM type 2 diabetes mellitus.
†Median (Q1-Q3).