Fig. 3.

Non-invasive liver fibrosis scores, insulin, and vitamin D levels in relation to liver fibrosis and development of HCC.

Comparison among patients without fibrosis (NO HCC-APRI <0.5) and those with liver fibrosis who will not develop HCC (NO HCC-APRI ≥0.5) or develop HCC (HCC-APRI ≥0.5). The box plots show the median (second quartile), first and third quartile, Tukey whiskers go 1.5 times the interquartile distance or to the highest or lowest point, whichever is shorter. Any data beyond these whiskers are shown as points. Comparisons were performed using one-way ANOVA test followed by Bonferroni’s post hoc test. Multiple comparison was performed by Student’s t test. Lowercase letter indicates significant difference with NO HCC-APRI <0.5 (a) and NO HCC-APRI ≥0.5 (b). APRI, AST-to-platelet ratio index; AST, aspartate aminotransferase; FIB-4, fibrosis-4; HCC, hepatocellular carcinoma.