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. 2022 Nov 30;25(1):39. doi: 10.3892/etm.2022.11738

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Copyright: © Kamiya et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Meclozine slightly augments the surface of osteoclasts in Hyp mice. (A) Representative histological images of distal femoral metaphysis stained with tartrate-resistant acid phosphatase in meclozine-treated and untreated Hyp mice. The purple signal indicates osteoclasts. Scale bars, 100 µm. (B) Oc.S and Oc.S/BS. Dots indicate the Oc.S and the Oc.S/BS of each sample, and bars indicate the mean ± SD. Statistical significance was analyzed by one-way ANOVA with post-hoc Tukey's honest significance test. ^*P<0.05. Hyp mice, X-linked hypophosphatemic mice; Oc.S, osteoclast surface; Oc.S/BS, osteoclast surface/bone surface.