Figure 3.

SDI-related differences of L-ADR in Mainland China. (A) The proportions of the national top three drug subclasses (antimicrobial, cardiovascular, and antineoplastic agents) in each province were indicated by the column width. The provinces were clustered into three groups (e.g., Low-middle, Middle and High-middle levels) according to WHO SDI quintile. There are no Low and High SDI levels of provinces in China. (B) Top 10 subclasses of chemical drugs-associated to DILI reports by SDI levels in Mainland China. CNS, central nervous system; NSAIDs, non-steroidal anti-inflammatory drugs.