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. 2022 May 13;12(12):4348–4364. doi: 10.1016/j.apsb.2022.05.007

Table 2.

Summary of phage therapy strategies.

Disease Pathogenic microbe Treatment drug Action mechanism
Superficial bacterial infections PA and Klebsiella pneumoniae
  • Thermosensitive hydrogel with IME-AB2 bacteriophages

  • LysGH15-API-Aquaphor (LAA) ointment

  • Liquid bacteriophage cocktail PYO

  • Clear the invading pathogens

  • Target drug-resistant bacteria

Diabetic wound healing Staphylococcus aureus, PA and Acinetobacter baumannii
  • Liquid bacteriophage cocktail

  • Liposome bacteriophage cocktail

  • Clear the invading pathogens

  • Avoid the production of inflammatory mediators

Burn wound infection PAKlebsiella pneumoniae
  • PA phagocytic monomer cocktails

  • Single bacteriophage (kpn 1, kpn 2, kpn 3, kpn 4 and kpn 5)

  • Clearing the invading pathogens

  • Avoid the production of inflammatory mediators

Tumor Tumor cells
  • Acteriophage-guided biotic-abiotic hybrid nanosystem

  • Tumor homologou angiogenin-binding bacteriophage-derived bionanofiber

  • Improve the immune status of cancer patients

  • Capture and block tumor derived angiopoietin to achieve tumor regression

  • Deliver other drugs as carriers