Table 2.

Adjusted odds ratios (ORs) for being on triple therapy, compared to not being on triple therapy, for patients with heart failure with reduced ejection fraction

Factor	Adjusted OR (95% CI)	P
Sex (ref: male)
Female	1.52 (1.46–1.59)	< 0.0001
Age (ref: 65–79), y
≥ 80	0.58 (0.56–0.60)	< 0.0001
Residence (ref: rural)
Urban	0.96 (0.91–1.01)	0.08
Income quintile (ref: Lowest 1)
2	1.07 (1.01–1.13)	0.02
3	1.08 (1.02–1.14)	< 0.01
4	1.04 (0.98–1.10)	0.24
Highest 5	1.08 (0.98–1.11)	0.16
Hospital type (ref: community)
Academic	1.15 (1.10–1.20)	< 0.0001
Comorbidity
Higher CCI score	0.91 (0.90–0.92)	< 0.0001
Other diuretics (ref: no)
Yes	1.69 (1.57–1.81)	< 0.0001
Calcium channel blockers (ref: no)
Yes	0.66 (0.64–0.69)	< 0.0001
Hydrochlorothiazide (ref: no)
Yes	0.79 (0.75–0.84)	< 0.0001
Rehospitalized within 6 mo of index discharge (ref: no)
Yes	1.41 (1.35–1.47)	< 0.0001

Multivariable logistic regressions were used.

CCI, Charlson Comorbidity Index; CI, confidence interval; HFrEF, heart failure with reduced ejection fraction; ref, referent.