Figure 1.

Kidney T cell transcriptome analysis of differentially expressed genes via Ingenuity Pathway Analysis (IPA) or Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis showed enrichment of pro-inflammatory pathways related to T cell signaling in disease-prone SS rats fed an animal-based diet. Conversely, kidney T cell derived from disease-protected SS rats fed a plant-based diet revealed enrichment of gene pathways primarily related to metabolic processes. Figure redrawn with permission from Abais-Battad et al [35].