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Sequence alignment of miR-34 family members and miR-34 target identification rates obtained by public prediction tools. (A) Sequence alignment of the mature miR-34a, miR-34b, and miR-34c. The seed-sequences are high-lighted in bold. A target mRNA with ideal seed-match binding site is shown in the bottom. (B) Overview of frequencies of predicted miR-34a, miR-34b, and miR-34c target mRNAs identified by the respective miRNA target prediction tools/algorithms.
